I don't have any good information so you can stop reading now...
My Dad swore up and down by natural oils. As a professional race engine builder, you had to put some weight behind his observations. However, synthetic oils have developed by leaps and bounds since he was building race engines. This is what I do know...
Between 1990 and 2001, I raced just about every weekend...somewhere. I also rode during the week "for training". I did oil changes and cleaned the filter every day I rode. I used Castrol GTX 20w50 in the bottom ends, some kind of specific foam filter oil and premixed Silcoline synthetic at 40:1. I would change the plug before any national or GNCC just because.
I had no oil related failures in that time. In 1998, I raced 48 events on the same piston/ring. When we tore down the bottom end, it looked new! (We big bored the top it was so bad!). I even had two events where the drain plug came out and dumped the oil in the forest somewhere. I finished 1st in one of those events and 3rd in the other.
I am not saying mineral is better than synthetic...but my guess is that it is not so much better that you should care. We live in a "throw away society". Do you really care if your piston lasts 5 minutes longer or your clutch lasts 1/3rd of a ride longer? Do you really care if your gears last 25 years? No. You plan to ride your bike 1, 3, or 5 years..sell it and buy the lastest weapon of choice.
I run synthetic now because I'm stupid. It is twice as expensive as mineral but I don't know what a brand of good mineral oil is so I don't want to chance it. I used to have good links for oil information. It is out there and not brand specific. (You probably need to be an engineer to understand it.) I'll see if I can dig it up or you can just Google like crazy!