I would just spend some time getting used to the twist throttle. Riding a bike is quite different than riding a quad, and it may be difficult to keep proper grip and control of the front brake when using a thumb throttle. It has been done before, but I am not quite certain of the specifics. A google search will probably turn something up for you. I'd guess all you really need is a set of ATV grips, and a thumb throttle to adapt. Might have to get creative on the cable stop, but I'm sure it wouldn't be too hard to figure something out.