Now that's pretty damn cool!
Building a bike interface should not be super difficult because in reality there are few controls. Throttle, front brake, clutch, handle bars, shift lever, rear brake.... the tougher part would be programing the movement of the "frame" of the bike.... and more importantly how that is mounted or controlled.
Something along the lines of a child's rocking horse, although there would be no gyroscopic effect....
It's cool to think about!
I am pretty sure you would need a pile of sensors for leaning, and hydraulics for the bouncing around of the bike, and, such, but i am sure it could be done